產(chǎn)品編號(hào) | bs-2433R |
英文名稱 | ATP4B Rabbit pAb |
中文名稱 | 氫鉀ATP酶通道蛋白抗體 |
別 名 | Gastric H(+)/K(+) ATPase subunit beta; H+K+ATPase; ATP4B; ATP6B; ATPase H+/K+exchanging beta polypeptide; ATPase H+/K+transporting beta polypeptide; Gastric H K ATPase catalytic subunit; Gastric H+/K+ATPase beta subunit; Gastric hydrogen potassium ATPase; Gastric hydrogen potassium ATPase beta; Hydrogen/potassium exchanging ATPase 4B; Potassium transporting ATPase beta chain; Potassium transporting ATPase subunit beta; Proton pump; Proton pump beta chain; ATP4B_HUMAN. |
![]() |
Specific References (1) | bs-2433R has been referenced in 1 publications.
[IF=12.282] Birkner K et al. β1-integrin-and KV 1.3 channel-dependent signaling stimulates glutamate release from Th17 cells. J Clin Invest. 2019 October 29. WB ; Human.
|
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號(hào) | |
交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Cow,Chicken,Dog) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 33 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ATP4B: 201-291/291 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008] Function: Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity. Subunit: Composed of two subunits: alpha (catalytic) and beta. Subcellular Location: Cell membrane Tissue Specificity: Expressed at highest levels in heart, skeletal Similarity: Belongs to the X(+)/potassium ATPases subunit beta family. SWISS: P51164 Gene ID: 496 Database links: Entrez Gene: 496 Human Entrez Gene: 11945 Mouse Omim: 137217 Human SwissProt: P51164 Human SwissProt: P50992 Mouse SwissProt: P18597 Rabbit Unigene: 434202 Human Unigene: 154039 Mouse Unigene: 10033 Rat |
產(chǎn)品圖片 | |