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ATP4B Rabbit pAb (bs-2433R)  
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產(chǎn)品編號(hào) bs-2433R
英文名稱 ATP4B Rabbit pAb
中文名稱 氫鉀ATP酶通道蛋白抗體
別    名 Gastric H(+)/K(+) ATPase subunit beta; H+K+ATPase; ATP4B; ATP6B; ATPase H+/K+exchanging beta polypeptide; ATPase H+/K+transporting beta polypeptide; Gastric H K ATPase catalytic subunit; Gastric H+/K+ATPase beta subunit; Gastric hydrogen potassium ATPase; Gastric hydrogen potassium ATPase beta; Hydrogen/potassium exchanging ATPase 4B; Potassium transporting ATPase beta chain; Potassium transporting ATPase subunit beta; Proton pump; Proton pump beta chain; ATP4B_HUMAN.  
Specific References  (1)     |     bs-2433R has been referenced in 1 publications.
[IF=12.282] Birkner K et al. β1-integrin-and KV 1.3 channel-dependent signaling stimulates glutamate release from Th17 cells. J Clin Invest. 2019 October 29.  WB ;  Human.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Pig,Cow,Chicken,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 33 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ATP4B: 201-291/291 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]

Function:
Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity.

Subunit:
Composed of two subunits: alpha (catalytic) and beta.

Subcellular Location:
Cell membrane

Tissue Specificity:
Expressed at highest levels in heart, skeletal

Similarity:
Belongs to the X(+)/potassium ATPases subunit beta family.

SWISS:
P51164

Gene ID:
496

Database links:

Entrez Gene: 496 Human

Entrez Gene: 11945 Mouse

Entrez Gene: 397131 Pig

Entrez Gene: 24217 Rat

Omim: 137217 Human

SwissProt: P51164 Human

SwissProt: P50992 Mouse

SwissProt: P18434 Pig

SwissProt: P18597 Rabbit

SwissProt: P18598 Rat

Unigene: 434202 Human

Unigene: 154039 Mouse

Unigene: 10033 Rat



產(chǎn)品圖片
Sample: Muscle (Mouse) Lysate at 40 ug Primary: Anti-ATP4B (bs-2433R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 33 kD Observed band size: 43 kD
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