| 產(chǎn)品編號 | bs-2572R |
| 英文名稱 | FPR1 Rabbit pAb |
| 中文名稱 | 甲酸基肽受體1抗體 |
| 別 名 | Formyl peptide receptor 1; fMet Leu Phe receptor; FMLP; FMLP Receptor; FPR 1; FPR; N formyl peptide chemoattractant receptor; N formyl peptide receptor; N formylpeptide chemoattractant receptor; fMet-Leu-Phe receptor; FMLPR; FPR; FPR receptor; FPR1; FPR1_HUMAN; N formylpeptide chemoattractant receptor; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor. |
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Specific References (3) | bs-2572R has been referenced in 3 publications.
[IF=6.6] Ana Paula Girol. et al. Annexin A1 Mimetic Peptide and Piperlongumine: Anti-Inflammatory Profiles in Endotoxin-Induced Uveitis. Cells-Basel. 2021 Nov;10(11):3170 IHC ; Rat.
[IF=4.26] Wang et al. Formylpeptide Receptors Promote the Migration and Differentiation of Rat Neural Stem Cells. (2016) Sci.Re. 6:25946 WB, IF(ICC) ; Rat.
[IF=4.12] Franken et al. Splenic red pulp macrophages are intrinsically superparamagnetic and contaminate magnetic cell isolates. (2015) Sci.Rep. 5:12940 FC/FACS ; Mouse.
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| 研究領(lǐng)域 | 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 39 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FPR1: 51-150/350 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010] Function: High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Neutrophils. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P21462 Gene ID: 2357 Database links: Entrez Gene: 2357 Human Omim: 136537 Human SwissProt: P21462 Human Unigene: 753 Human 轉(zhuǎn)錄調(diào)節(jié)因子（Transcriptin Regulators） FPR1屬于G蛋白偶聯(lián)受體家族成員，參與細(xì)胞信號傳導(dǎo)，激活MAPK通路，免疫應(yīng)答。 |
| 產(chǎn)品圖片 |
Sample:
Lane 1: U87MG (Human) Cell Lysate at 30 ug
Lane 2: U251 (Human) Cell Lysate at 30 ug
Lane 3: U937 (Human) Cell Lysate at 30 ug
Lane 4: SW480 (Human) Cell Lysate at 30 ug
Primary: Anti-FPR1 (bs-2572R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60 kD
Observed band size: 60 kD
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