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KIF17 Rabbit pAb (bs-3527R)  
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產(chǎn)品編號(hào) bs-3527R
英文名稱 KIF17 Rabbit pAb
中文名稱 驅(qū)動(dòng)蛋白家族KIF17抗體
別    名 KIAA1405; KIF 17; KIF 17B; KIF 3X; KIF17B; KIF3-related motor protein; KIF3X; Kinesin family member 17; Kinesin like protein KIF 17; Kinesin like protein KIF17; KIF17_HUMAN.  
研究領(lǐng)域 腫瘤  免疫學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human (predicted: Mouse,Rat,Pig,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 115 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KIF17: 201-300/1029 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The kinesin superfamily of proteins (KIFs) consists of a class of microtubule-dependent motors that play a major role in many cellular and developmental functions, including organelle transport, mitosis, meiosis, and possibly long-range signaling in neurons. The kinesin proteins are involved in organelle transport and are primarily associated with anterograde transport of vesicles and organelles in neurons, epithelial cells, and melanosomes with bidirectional transport of mitochondria. They also mediate transport between the endoplasmic reticulum (ER) and the Golgi complex. In neurons, kinesin motors conduct vesicular transport, such as of synaptic vesicle components to axons and of neurotransmitter receptors to dendrites. KIF17 belongs to the functionally diverse subgroup of the kinesin superfamily characterized by a N-terminal motor domain (N-IV class), that includes the KIF3 motor protein. KIF17 is specifically expressed in the brain, present in abundance in the gray matter, particularly in the hippocampus and cerebral cortex, but not in the white matter such as the optic nerve.

Function:
Transports vesicles containing N-methyl-D-aspartate(NMDA) receptor 2B along microtubules (By similarity).

Subunit:
Interacts with LIN-10 PDZ domain. Interacts with PIWIL1(By similarity). Interacts with TBATA (By similarity).

Subcellular Location:
Cytoplasm, cytoskeleton (Probable).

Similarity:
Belongs to the kinesin-like protein family.
Contains 1 kinesin-motor domain.

SWISS:
Q9P2E2

Gene ID:
57576

Database links:

Entrez Gene: 57576 Human

Entrez Gene: 16559 Mouse

Omim: 605037 Human

SwissProt: Q9P2E2 Human

SwissProt: Q99PW8 Mouse

Unigene: 130411 Human

Unigene: 271936 Mouse



產(chǎn)品圖片
Sample: HepG2 Cell Lysate at 30 ug Primary: Anti-KIF17 (bs-3527R) at 1:300 dilution; Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bse-0295G-HRP) at 1: 5000 dilution; Predicted band size :115 kD Observed band size :115 kD
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