| 產(chǎn)品編號(hào) | bs-3662R |
| 英文名稱 | WNT10B Rabbit pAb |
| 中文名稱 | 信號(hào)通路WNT10B抗體 |
| 別 名 | WN10B_HUMAN; SHFM6; wingless type MMTV integration site family, member 10B; wnt12; WNT10-B. |
 |
Specific References (6) | bs-3662R has been referenced in 6 publications.
[IF=5.5] Zhang et al. Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling. (2016) Cell.Physiol.Biochem. 39:360-70 IHC ; Human.
[IF=4.65] Zhang, H., et al. "Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling."Cellular Physiology and Biochemistry 39.1 (2016): 360-370. WB ; Human.
[IF=3.553] Li M et al. Plant MIR156 Regulates Intestinal Growth in Mammals by Targeting the Wnt/β-catenin Pathway. Am J Physiol Cell Physiol. 2019 Jun 5. IHF&ICF ; Mouse&Pig.
[IF=1.597] Liya Bai. et al. DNA methylation and histone acetylation are involved in Wnt10b expression during the secondary hair follicle cycle in Angora rabbits. 2021 Jan 06 IHC ; Rabbit.
[IF=1.07] Ke, Jin, et al. "Erbium: YAG laser (2,940 nm) treatment stimulates hair growth through upregulating Wnt 10b and β-catenin expression in C57BL/6 mice." International Journal of Clinical and Experimental Medicine 8.11 (2015): 20883. WB ; Mouse.
[IF=1.03] Lu, Juan, et al. "Expression of Wnt3a, Wnt10b, β-catenin and DKK1 in periodontium during orthodontic tooth movement in rats." Acta Odontologica Scandinavica (2015): 1-7. IHC-P ; Rat.
|
| 研究領(lǐng)域 | 腫瘤 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 40 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human WNT10B: 201-300/389 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008] Subcellular Location: Secreted, extracellular space, extracellular matrix. Tissue Specificity: Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain. Similarity: Belongs to the Wnt family. SWISS: O00744 Gene ID: 7480 Database links: Entrez Gene: 7480 Human Entrez Gene: 22410 Mouse Omim: 601906 Human SwissProt: O00744 Human SwissProt: P48614 Mouse Unigene: 91985 Human Unigene: 4709 Mouse |
