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PAR3 Rabbit pAb (bs-9510R)  
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產(chǎn)品編號(hào) bs-9510R
英文名稱 PAR3 Rabbit pAb
中文名稱 蛋白酶激活受體3抗體
別    名 Proteinase Activated Receptor 3; coagulation factor II(thrombin) receptor-like 2; Coagulation factor II receptor-like 2; F2RL2; PAR 3; PAR-3; PAR3; PAR3_HUMAN; protease activated receptor3; Proteinase-activated receptor 3; thrombin receptor like 2; Thromb  
Specific References  (2)     |     bs-9510R has been referenced in 2 publications.
[IF=2.272] Liu et al. Effect of evodiamine and berberine on miR-429 as an oncogene in human colorectal cancer. (2016) Onco.Targets.Ther. 9:4121-7  WB ;  Human.  
[IF=1.56] Huang, Chao, et al. "Analysis of different components in the peritumoral tissue microenvironment of colorectal cancer: A potential prospect in tumorigenesis. Corrigendum in/10.3892/mmr. 2016.5882." Molecular Medicine Reports 14.3 (2016): 2555-2565.  IHC-P ;  Human.  
研究領(lǐng)域 心血管  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 42 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PAR3: 121-220/374 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
Tissue specificity:
Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.

Function:
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.

Post-translational modifications:
A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
O00254

Gene ID:
2151

Database links:

Entrez Gene: 2151 Human

Omim: 601919 Human

SwissProt: Q58D85 Cow

SwissProt: O00254 Human

Unigene: 24447 Cow

Unigene: 136948 Human

Unigene: 42502 Human



產(chǎn)品圖片
Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti- PAR3 (bs-9510R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 57 kD
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