| 產(chǎn)品編號(hào) | bs-11005R |
| 英文名稱 | FAM64A Rabbit pAb |
| 中文名稱 | 染色體分離調(diào)節(jié)蛋白1抗體 |
| 別 名 | FA64A_HUMAN; FAM64A; family with sequence similarity 64, member A; FLJ10156; FLJ10491; Protein FAM64A; RCS1; regulator of chromosome segregation 1; PIMREG; CALM-interactor expressed in thymus and spleen; PICALM-interacting mitotic regulator; Regulator of chromosome segregation protein 1; |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Pig,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 27 kDa |
| 檢測(cè)分子量 | |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RCS1/FAM64A: 151-248/248 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
PIMREG (PICALM Interacting Mitotic Regulator) is a Protein Coding gene. Diseases associated with PIMREG include Suppurative Periapical Periodontitis. Function: During mitosis, may play a role in the control of metaphase-to-anaphase transition. Subunit: Isoform 1 and isoform 2 interact with PICALM; this interaction may target PICALM to the nucleus (PubMed:16491119). During mitosis, associates with HDAC2 and MTA2 subunits of the chromatin-remodeling NuRD complex; this association is strongest at prometaphase and decreases as the cell progresses through metaphase and anaphase (PubMed:18757745). Subcellular Location: Nucleus Tissue Specificity: Expressed in thymus (at protein level). Detected in spleen, colon, ovary and small intestines. Post-translational modifications: Ubiquitinated by the anaphase-promoting complex/cyclosome (APC/C) complex in the presence of FZR1, leading to its degradation by the proteasome during mitotic exit. However, degradation is not essential for normal mitotic progression within a single cell cycle. SWISS: Q9BSJ6 Gene ID: 54478 Database links: Entrez Gene: 54478 Human SwissProt: Q9BSJ6 Human Unigene: 592116 Human |
| 產(chǎn)品圖片 |
Sample:
Thymus (Mouse) Lysate at 40 ug
Spleen (Mouse) Lysate at 40 ug
Primary: Anti- FAM64A (bs-11005R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 25 kD
Sample:
Ovary (Mouse) Lysate at 40 ug
Primary: Anti- FAM64A (bs-11005R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 27/26 kD
Sample:
Thymus(Mouse) Lysate at 40 ug
Primary: Anti- FAM64A (bs-11005R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 27/26 kD
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