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FCN1 Rabbit pAb (bs-16061R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16061R
英文名稱 FCN1 Rabbit pAb
中文名稱 FCN1蛋白抗體
別    名 Collagen/fibrinogen domain containing protein 1; Collagen/fibrinogen domain-containing protein 1; Fcn1; FCN1_HUMAN; FCNM; ficolin(collagen/fibrinogen domain containing) 1; Ficolin 1; Ficolin A; Ficolin alpha; Ficolin-1; Ficolin-A; Ficolin-alpha; M ficolin; M-ficolin.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) (predicted: Human,Mouse,Rat)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 32 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FCN1: 101-200/326 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq, Jul 2008]

Subunit:
Involved in serum exerting lectin activity. Binds GlcNAc.

Subcellular Location:
Secreted. Found on the monocyte surface.

Tissue Specificity:
Peripheral blood leukocytes. Also detected in spleen, lung, and thymus, may be due to the presence of tissue macrophages or trapped blood in these tissues. Not detected on lymphocytes and granulocytes.

Similarity:
Belongs to the ficolin lectin family.
Contains 1 collagen-like domain.
Contains 1 fibrinogen C-terminal domain.

SWISS:
O00602

Gene ID:
2219

Database links:

Entrez Gene: 2219 Human

Entrez Gene: 14133 Mouse

Entrez Gene: 83517 Rat

Omim: 601252 Human

SwissProt: O00602 Human

SwissProt: O70165 Mouse

SwissProt: Q9WTS8 Rat

Unigene: 440898 Human

Unigene: 10510 Mouse

Unigene: 20051 Rat



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