產(chǎn)品編號(hào) | bs-16061R |
英文名稱 | FCN1 Rabbit pAb |
中文名稱 | FCN1蛋白抗體 |
別 名 | Collagen/fibrinogen domain containing protein 1; Collagen/fibrinogen domain-containing protein 1; Fcn1; FCN1_HUMAN; FCNM; ficolin(collagen/fibrinogen domain containing) 1; Ficolin 1; Ficolin A; Ficolin alpha; Ficolin-1; Ficolin-A; Ficolin-alpha; M ficolin; M-ficolin. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號(hào) | |
交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 32 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FCN1: 101-200/326 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq, Jul 2008] Subunit: Involved in serum exerting lectin activity. Binds GlcNAc. Subcellular Location: Secreted. Found on the monocyte surface. Tissue Specificity: Peripheral blood leukocytes. Also detected in spleen, lung, and thymus, may be due to the presence of tissue macrophages or trapped blood in these tissues. Not detected on lymphocytes and granulocytes. Similarity: Belongs to the ficolin lectin family. Contains 1 collagen-like domain. Contains 1 fibrinogen C-terminal domain. SWISS: O00602 Gene ID: 2219 Database links: Entrez Gene: 2219 Human Entrez Gene: 14133 Mouse Omim: 601252 Human SwissProt: O00602 Human SwissProt: O70165 Mouse Unigene: 440898 Human Unigene: 10510 Mouse Unigene: 20051 Rat |