| 產(chǎn)品編號(hào) | bs-16225R |
| 英文名稱(chēng) | GALNTL1 Rabbit pAb |
| 中文名稱(chēng) | GalNAc-TL1蛋白抗體 |
| 別 名 | GalNAc T like protein 1; GALNACT16; GALNT16; GLT16_HUMAN; Human GalNAc T16 DNA sequence; KIAA1130; mpp-GalNAc-T16; N acetylgalactosaminyltransferase like protein 1; Polypeptide GalNAc transferase like protein 1; polypeptide N acetylgalactosaminyltransferase 16; pp GaNTase like protein 1; Protein UDP acetylgalactosaminyltransferase like protein 1 3 UDP GalNAc : polypeptide; UDP N acetyl alpha D galactosamine : polypeptide N acetylgalactosaminyltransferase like 1; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 1. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 63 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GALNTL1: 51-150/558 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosaminyl) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-TL1 (UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1), also known as GALNT16, is a 588 amino acid single-pass type II membrane protein belonging to the glycosyltransferase 2 family, which localizes to the Golgi apparatus. GalNAc-TL1 utilizes manganese and calcium as cofactors, and catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, which involves the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Containing one ricin B-type lectin domain, GalNAc-TL1 exists as two alternatively spliced isoforms. Function: GALNTL1 belongs to the glycosyltransferase 2 family, GalNAc-T subfamily. It contains 1 ricin B type lectin domain. GALNTL1 may catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Subcellular Location: Golgi apparatus membrane; Single pass type II membrane protein Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. Contains 1 ricin B-type lectin domain. SWISS: Q8N428 Gene ID: 57452 Database links: Entrez Gene: 57452 Human Entrez Gene: 108760 Mouse SwissProt: Q8N428 Human SwissProt: Q9JJ61 Mouse |
