產(chǎn)品編號(hào) | bs-18854R |
英文名稱(chēng) | METTL8 Rabbit pAb |
中文名稱(chēng) | 甲基化樣蛋白8抗體 |
別 名 | tension induced inhibited protein; methyltransferase like 8; methyltransferase like protein 8; TIP. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
克 隆 號(hào) | |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 32 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human METTL8: 1-100/291 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
METTL8 is a 291 amino acid cytoplasmic and nuclear protein that exists as multiple alternatively spliced isoforms and is thought to function as a methyltransferase. METTL8 is a member of the methyltransferase superfamily, which includes DNA methyltransferases (Dnmt), histone methyltransferases, catechol-O-methyl transferases and many others. Members of the methyltransferase superfamily have enzymatic activity that results in the transfer of a methyl group to and from DNA, RNA or amino acids. METTL8 is encoded by a gene located on human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Function: Probable methyltransferase Subunit: Interacts with EP300 Subcellular Location: Cytoplasmic and Nuclear Similarity: Belongs to the methyltransferase superfamily. METL family. SWISS: Q9H825 Gene ID: 79828 Database links: Entrez Gene: 79828 Human SwissProt: Q9H825 Human Unigene: 135146 Human |