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PECI Rabbit pAb (bs-12611R)  
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產(chǎn)品編號(hào) bs-12611R
英文名稱 PECI Rabbit pAb
中文名稱 PECI蛋白抗體
別    名 2-trans-enoyl-CoA isomerase; ACBD2; acyl Coenzyme A binding domain containing 2; D2-enoyl-CoA isomerase; D3; D3 D2 enoyl CoA isomerase; DBI related protein 1; DBI-related protein 1; delta(2)-enoyl-CoA isomerase; delta(3); delta(3) delta(2) enoyl CoA isome  
研究領(lǐng)域 腫瘤  細(xì)胞生物  結(jié)合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat (predicted: Human,Mouse,Pig,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 39 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PECI: 211-310/394 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011]

Function:
Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates.

Subcellular Location:
Mitochondrion and Peroxisome matrix.

Tissue Specificity:
Abundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells.

Similarity:
In the C-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
Contains 1 ACB (acyl-CoA-binding) domain.

SWISS:
O75521

Gene ID:
10455

Database links:

Entrez Gene: 10455 Human

Entrez Gene: 23986 Mouse

Entrez Gene: 291075 Rat

Omim: 608024 Human

SwissProt: O75521 Human

SwissProt: Q9WUR2 Mouse

SwissProt: Q5XIC0 Rat

Unigene: 15250 Human

Unigene: 28883 Mouse

Unigene: 108029 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Rat skeletal muscle); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PECI) Polyclonal Antibody, Unconjugated (bs-12611R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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