產(chǎn)品編號(hào) | bs-12611R |
英文名稱 | PECI Rabbit pAb |
中文名稱 | PECI蛋白抗體 |
別 名 | 2-trans-enoyl-CoA isomerase; ACBD2; acyl Coenzyme A binding domain containing 2; D2-enoyl-CoA isomerase; D3; D3 D2 enoyl CoA isomerase; DBI related protein 1; DBI-related protein 1; delta(2)-enoyl-CoA isomerase; delta(3); delta(3) delta(2) enoyl CoA isome |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 結(jié)合蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Rat (predicted: Human,Mouse,Pig,Chicken,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 39 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PECI: 211-310/394 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011] Function: Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates. Subcellular Location: Mitochondrion and Peroxisome matrix. Tissue Specificity: Abundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells. Similarity: In the C-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. Contains 1 ACB (acyl-CoA-binding) domain. SWISS: O75521 Gene ID: 10455 Database links: Entrez Gene: 10455 Human Entrez Gene: 23986 Mouse Omim: 608024 Human SwissProt: O75521 Human SwissProt: Q9WUR2 Mouse Unigene: 15250 Human Unigene: 28883 Mouse Unigene: 108029 Rat |
產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Rat skeletal muscle); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PECI) Polyclonal Antibody, Unconjugated (bs-12611R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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