| 產(chǎn)品編號(hào) | bs-2482R-Cy5 |
| 英文名稱 | Rabbit Anti-MIP3/CCL23/Cy5 Conjugated antibody |
| 中文名稱 | Cy5標(biāo)記的巨噬細(xì)胞炎性蛋白抗體 |
| 別 名 | MIP3; MIP 3; MIP-3; C-C motif chemokine 23; Macrophage Inflammatory Protein 3; hMIP-3; C6 beta chemokine; CCL 23; CCL23; Chemokine (C C motif) ligand 23; Chemokine CC motif ligand 23; ck beta 8; CKB 8 ; Ckb-8-1; CKB8; CKbeta8; Hmrp-2a; hmrp2a; macrophage inflammatory protein 3; MIP 3; MIP3; MPIF 1; MPIF1; Myeloid progenitor inhibitory factor 1; OTTHUMP00000163948; SCYA 23; SCYA23; Small inducible cytokine A 23; Small inducible cytokine subfamily A (Cys Cys) member 23; Small inducible cytokine subfamily A (Cys-Cys), member 23; Small inducible cytokine subfamily A, member 23; chemokine. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Pig, Cow, Horse, Guinea Pig, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 11kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CCL23 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013] Function: Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. Subcellular Location: Secreted. Tissue Specificity: High levels in adult lung, liver, skeletal muscle and pancreas. Moderate levels in fetal liver, adult bone marrow and placenta. The short form is the major species and the longer form was detected only in very low abundance. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are found in high levels in synovial fluids from rheumatoid patients. Similarity: Belongs to the intercrine beta (chemokine CC) family. Database links: Entrez Gene: 6368 Human Omim: 602494 Human SwissProt: P55773 Human Unigene: 169191 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
