| 產(chǎn)品編號(hào) | bs-10732R-PE-Cy5 |
| 英文名稱 | Rabbit Anti-MARCH10/PE-Cy5 Conjugated antibody |
| 中文名稱 | PE-Cy5標(biāo)記的膜相關(guān)環(huán)指蛋白10抗體 |
| 別 名 | MARCH 10; MARCH X; MARCH-X; MARCH10; MARHA_HUMAN; Membrane associated ring finger (C3HC4) 10; Membrane associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase ; Membrane associated ring finger 10; Membrane associated RING finger protein 10; Membrane-associated RING finger protein 10; Membrane-associated RING-CH protein X; Probable E3 ubiquitin protein ligase MARCH10; Probable E3 ubiquitin-protein ligase MARCH10; Ring finger protein 190; RNF 190; RNF190. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 91kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MARCH10 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. MARCH10 (membrane-associated ring finger (C3HC4) 10), also known as RNF190 (ring finger protein 190) or MARCH-X, is an 808 amino acid protein with one RING-CH-type zinc finger domain. MARCH10 may function as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation. Function: E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. Similarity: Contains 1 RING-CH-type zinc finger. Database links: Entrez Gene: 162333 Human Omim: 613337 Human SwissProt: Q8NA82 Human Unigene: 665663 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
